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Multi-target kinase inhibitor 2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-149636
    Multi-target kinase inhibitor 2

    		EGFR CDK VEGFR Cancer
    Multi-target kinase inhibitor 2 (compound 5K) is a multi-targeted kinase inhibitor, and exhibits activity against EGFR, Her2, VEGFR2, and CDK2 enzymes, with IC50 values ranging from 40 to 204 nM. Multi-target kinase inhibitor 2 shows cytotoxic effects were observed against HepG2, HeLa , MDA-MB-231 and MCF-7, with IC50 of 41, 57, 51 and 59 μM. Multi-target kinase inhibitor 2 induces cell cycle arrest and apoptosis in HepG2 cells.
    <em>Multi-target</em> <em>kinase</em> <em>inhibitor 2</em>

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